The FA Cup is back this weekend with the semi-finals!
Read on to find out all the latest news ahead of the domestic clash between City and the Blues.
Here's how we think the teams will lineup in a bid to book their place in the FA Cup Final.
Chelsea Predicted 11
Chelsea manager Thomas Tuchel has confirmed that Mateo Kovacic will miss his side's FA Cup semi-final with Manchester City at Wembley on Saturday.
Reece James is expected to keep his place on the right over Callum Hudson-Odoi, but Marcos Alonso has plenty of experience playing at Wembley, so he could be rotated in for Ben Chilwell on the opposite side.
Mason Mount is undroppable at the moment, but Christian Pulisic is another player that Tuchel needs to be careful over given his recent fitness woes, so Timo Werner is a candidate to start over the American, who played the full 90 in midweek.
Man City Predicted 11
Zack Steffen has proved his worth in goal during the previous rounds, but Guardiola may elect to start Ederson given the magnitude of this game, while Joao Cancelo should certainly earn a recall to the defence.
The Portuguese full-back could be shifted out to the left as Kyle Walker keeps his place on the right-hand side, while Aymeric Laporte shook off a minor injury to make the bench in midweek and is in contention to replace John Stones against Chelsea.
Kevin De Bruyne boasts four goals and five assists from his last eight FA Cup appearances and will hope to get one over his former club at the home of English football.
Chelsea vs Man City Semi-Final Date / Kick-off Time
Both of this season's FA Cup semi-finals will be held at Wembley Stadium and will go to extra-time and penalties if the scores are level after 90 minutes and extra time.
The FA Cup semi-final between Chelsea and Man City will take place on Saturday, 17 April, with the action set to kick-off at 5:30pm BST / 12:30pm EST.
How to watch Chelsea vs Man City
Both FA Cup semi-finals will be shown live on BBC One, which is available to all viewers in the UK.
The game, a repeat of the 2018 final, will also be streamed on BBC iPlayer and online, with various commentary options.
BBC Chelsea vs Man City Schedule
Emirates FA Cup Semi-Final - Coverage to start from 4:30pm on Saturday, 17 April (BBC One)
All times UK
How to watch FA Cup Semi-Finals in the USA
FA Cup matches can be seen exclusively on ESPN+ in the US.
Both semi-finals will be streamed live in English and Spanish.
ESPN+ will also provide highlights and analysis of FA Cup games throughout the weekend on its "ESPN FC" show, including a special recap edition on Sunday, 18 April.
An ESPN+ subscription will cost you $5.99 per month or $59.99 annually.
It can also be bundled in with Disney+ and Hulu for $12.99 per month, or you can choose to remove the ads on Hulu for $18.99 per month.
The Premier League leaders lost for only the second time in 29 games in all competitions on Saturday as they were beaten 2-1 after Guardiola made seven changes to the side.
Man City will still be confident going into the FA Cup semi-final, having dominated nearly all domestic opponents this season.
Last six games: WWWWWL
Latest outing: Manchester City 1-2 Leeds United, 10/04
Despite having lost to Conceicao's Porto in their last outing, Chelsea still progressed through to the Champions League semi-finals.
Thomas Tuchel will be confident that his side can cause an upset against the soon to be Premier League Champions.
Last six games: WDLWWL
Latest outing: Chelsea 0-1 Porto, 13/04