NFL DFS: DraftKings Week 4 lineup advice - start/sit, stack options, QB, cheap backs, & more

Another NFL weekend is waiting for us. Week 4 has more than a few big matchups, and that creates opportunities for DFS players!

Let's dive into this week and see where there is profit to be made.

We will be focusing on the early slate of games. With 10 1pm ET games that window offers the most variance, and therefore a good chance of walking away with wins!

This advice is based on DraftKings scoring & pricing.

Week 4 stack

The QB/WR stack is a deadly combo, so who are the best options this week?

Expensive stack

The best one to go all-in with this week is Kyler Murray ($7k) & DeAndre Hopkins ($8.5k).

madden 21 kyler murray
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ON THE MOVE: Murray's incredible rushing has made him a fantasy beast this year

The Cardinals duo has been laying waste to defenses over the first three weeks. Hopkins leads the NFL with 356 receiving yards while Murray has already picked up 187 yards and four TDs on the ground.

There is risk here as Hopkins hasn't practiced all week with an ankle injury, so keep an eye on developments if you want to run this stack.

Bargain stack

There aren't many great choices for a cheap QB, but one that stands out is Baker Mayfield ($5.8k). The Browns haven't been amazing through the air, but they are facing a Cowboys team that is struggling to slow offenses down.

With Baker then, comes the clear choice of Jarvis Landry ($5.1k) at WR. With 12 catches on 13 targets he is picking up good yardage. If he finds the endzone this stack will be a killer combo.

Running backs

With Christian McCaffrey on IR and the Titans-Steelers game postponed there are some tough choices at RB this week.

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DO IT ALL: Kamara is 5th in RECEIVING yards!

Alvin Kamara ($8k) IS the Saints offense right now. The whole show runs through him and defenses are struggling to slow him down.

Houston currently sit 24th in rush defense DVOA, so Dalvin Cook ($7.6k) is another of the elite backs that you should consider this week.

Cheap backs

Myles Gaskin ($5k) is locking down the Dolphins backfield, but the vulturing of Jordan Howard could cause some problems.

Nyheim Hines ($4.7k) continues to see solid touches as the receiving option in Indy.

If you want to go really cheap then Gus Edwards ($4k) is an interesting choice. The Ravens should put away Washington pretty quickly, giving Edwards plenty of garbage time carries to rack up yards.

Wide receiver

The Seattle pair of Tyler Lockett ($7k) and DK Metcalf ($6.8k) are the safest bets as Russ keeps cooking.

Tyler Boyd ($6.1k) is a tempting player against a poor Jacksonville pass defense.

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HOLD THE BALL: Metcalf messed up big time last week

The return of Kenny Golladay ($6k) is an interesting one, but the Saints are likely to focus their plans on stopping him.

Cheap options

Andy Isabella ($4.5k) is getting more involved and if Hopkins can't play then he could easily outperform that price tag.

Cedrick Wilson ($3.2k) had a massive game last week but the Dallas receiver corps is so deep he could easily disappear this time around.

Tight end

The TE position is always something of a shot in the dark.

You're basically hunting touchdowns, and that is made trickier by Jonnu Smith and Eric Ebron being sidelined.

gronkowski madden 21
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WILL THE REAL GRONK PLEASE STAND UP: It's been a poor return to the NFL

Jimmy Graham ($3.8k) is a nice option after getting a TD from both Trubisky & Foles last week.

The Rob Gronkowski ($3.6k) explosion might be coming, but the risk is that he goes back to zero catches this week.

In the end, Dalton Schultz ($4.3k) might be the best option here.


The Ravens ($4k) are the clear #1 as they will look to suffocate Dwayne Haskins and the Washington offense.

Seattle ($3.4k) are also a good shout to clamp down on the Dolphins.

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